Exogenous surfactant therapy in pediatrics
نویسندگان
چکیده
منابع مشابه
[Exogenous surfactant therapy in pediatrics].
OBJECTIVE To review current knowledge about the use of exogenous surfactants in the treatment of different lung diseases causing acute respiratory failure in children. SOURCE OF DATA This review is based on the author's experience and on recent data retrieved from ONIA, Mdconsult, Medline and the Cochrane Database Library. SUMMARY OF THE FINDINGS In spite of the success of the use of exogen...
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Exogenous surfactant therapy has an established role in the management of neonatal respiratory distress syndrome (RDS). This article summarises the current evidence on surfactant therapy. The use of surfactant for the treatment or prophylaxis of neonatal RDS results in a 30% to 65% relative reduction in the risk of pneumothorax and up to a 40% relative reduction in the risk of mortality. Advers...
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Since the identification of surfactant deficiency as the putative cause of the infant respiratory distress syndrome (RDS) by Avery and Mead in 1959, our understanding of the role of pulmonary surfactant in respiratory physiology and the pathophysiology of acute lung injury (ALI) has advanced substantially. Surfactant replacement has become routine for the prevention and treatment of infant RDS...
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perception that we represented the regime and were its mouthpiece; that the situation was more sensitive than we had realised; that feelings of hurt and anguish ran deep; that we had in fact been resigned to accepting an atrocious situation. I apologised for this complacency, for the loss of dignity our colleagues had suffered for so long, and for all our errors of omis~ion, and expressed the h...
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Since the Food and Drug Administration (FDA) approved exogenous surfactant in the early 90s for the treatment of neonates with Hyaline Membrane Disease (HMD), many studies have focused on enlarging its indications for others types of lung injuries and for other age groups. Although in the past 20 years no studies have shown clear results about the efficacy of exogenous surfactant treatment in p...
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ژورنال
عنوان ژورنال: Jornal de Pediatria
سال: 2003
ISSN: 0021-7557
DOI: 10.2223/jped.1097